Visual Function Decline Resulting from Geographic Atrophy

Ovarian atrophy resulting from urethane injection of neonatal mice.

Treatment of neonatal mice with urethane (0-5 or 0-75 mg/g body wt, i.p.) caused a lack of follicular development beyond the primordial stage. An effect of the thymus on ovarian development is inferred.

Geographic atrophy and cardiovascular disease.

We read with great interest the article by Fleckenstein et al. on the association of the diffuse-trickling (DT) phenotype of geographic atrophy (GA) with cardiovascular disease (CVD), with possible significance for choroidal vascular compromise. We wish to make the readership of IOVS aware that our group has published several relevant observations about the relation among reticular macular dise...

Protection of Cells from Degeneration and Treatment of Geographic Atrophy

Altered peripheral nerve function resulting from haemodialysis.

The amplitudes of muscle and nerve action potentials evoked median nerve stimulation were recorded just before and immediately after haemodialysis. These revealed a growht of action potential amplitude during dialysis. It is suggested that some component of the defective peripheral nerve function that inevitably accompanies uraemia is temporarily improved during dialysis.

Enlargement of atrophy and visual acuity loss in the geographic atrophy form of age-related macular degeneration.

OBJECTIVE To describe the progression of geographic atrophy (GA) from age-related macular degeneration (AMD) with respect to visual acuity (VA) loss and enlargement of atrophy. DESIGN A prospectively observed case series. SETTING Tertiary retinal referral center. PARTICIPANTS One hundred twenty-three patients with GA due to AMD who completed at least 1 year of follow-up (median follow-up,...